Effects of the aqueous extract of Pycnanthus angolensis (Myristicaceae) on male rat sexual behavior and nitric oxide release

Erectile dysfunction is a major public health problem leading to harmful consequences for couples. Hence the need find adequate treatments using medicinal plants such as Pycnanthus angolensis, Cameroonian plant used treat erectile dysfunction. The effects of aqueous extract angolensis wood were evaluated on male rat sexual behavior and nitric oxide release. Adult Wistar rats divided into 4 groups 5 each that included group receiving orally: distilled water (10 ml/Kg BW), treatment (43 or 86 172 mg/kg BW). Sexual behaviors monitored days 1, 4, 7, 14 by pairing receptive females levels assessed in penile homogenate. At end treatment, killed organs weighed. No significant effect was observed weights. When administered at dose 43 mg/Kg, body weight; significantly increased (p<0.05) performance well libido rats. Nitric release extract-treated rats, while compared control group. study demonstrates which can enhance rat. Hence, it be management dysfunction, mainly weight.